This sweet Southern belle has it all: beauty, brains, and talent. The charming actress, who started off her career in the theater, has starred in movies such as Fried Green Tomatoes, Grand Canyon, Bullets Over Broadway, and Boys on the Side. She returned to the stage to star in Proof, for which she won the Tony award. Parker now stars in the Showtime series Weeds as a drug-dealing working mom. She and her ex-boyfriend Billy Crudup have one child together. Parker adopted an African baby in 2007.